Immediate-type hypersensitivity reaction to Mannitol as drug excipient (E421): a case report.

نویسندگان

  • G F Calogiuri
  • L Muratore
  • E Nettis
  • A M Casto
  • E Di Leo
  • A Vacca
چکیده

Allergic reactions to mannitol have been reported rarely, despite its widespread use as a drug and as a food excipient. This is the first case report in which oral mannitol induces an immediate type hypersensitivity as a drug excipient, in a 42 year old man affected by rhinitis to olive tree pollen. Unusual and undervalued risk factors for mannitol hypersensitivity are examined.

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عنوان ژورنال:
  • European annals of allergy and clinical immunology

دوره 47 3  شماره 

صفحات  -

تاریخ انتشار 2015